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Articles 
Kathleen Squires, Anton L. Pozniak, Gerald Pierone, Jr., Corklin R. Steinhart, Daniel Berger, Nicholaos C. Bellos, Stephen L. Becker, Michael Wulfsohn, Michael D. Miller, John J. Toole, Dion F. Coakley, Andrew Cheng for the Study 907 Team* In treatment-experienced patients with suboptimal viral suppression, tenofovir disoproxil fumarate significantly reduced HIV-1 RNA levels and had a safety profile similar to that of placebo.
Michael B. Rothberg, Sandra Bellantonio, and David N. Rose For unvaccinated or high-risk vaccinated patients during the influenza season, treating with oseltamivir without previous testing is cost-effective. For other patients, rapid testing for influenza followed by treatment with oseltamivir is cost-effective. Empirical amantadine treatment is a low-cost alternative to oseltamivir.
David T. Felson, Sara McLaughlin, Joyce Goggins, Michael P. LaValley, M. Elon Gale, Saara Totterman, Wei Li, Catherine Hill, and Daniel Gale Bone marrow edema on magnetic resonance imaging of the knee predicts subsequent deterioration of knee osteoarthritis. Bone marrow edema is associated with limb malalignment, which partially explains its relation to progressive knee damage.
Nathaniel Hupert, Gonzalo M.L. Bearman, Alvin I. Mushlin, and Mark A. Callahan Although the clinical features of inhalational anthrax overlap with those of common viral respiratory infections, some features are characteristic of anthrax. A triage algorithm based on these features may help to diagnose presumptive inhalational anthrax in the setting of a large-scale anthrax attack.
Brief Communications
Luca Chiovato, Francesco Latrofa, Lewis E. Braverman, Furio Pacini, Marco Capezzone, Lucio Masserini, Lucia Grasso, and Aldo Pinchera In patients with autoimmune thyroiditis, antibodies to all major thyroid antigens gradually disappear after complete ablation of thyroid tissue. This finding is evidence that production of autoantibody requires the continuing presence of autoantigen.
Reviews
Peter J. Barnes and Ian M. Adcock Recent discoveries about gene transcription have advanced our understanding of the molecular mechanisms of corticosteroid suppression of inflammation.
Lin H. Chen, Elizabeth D. Barnett, and Mary E. Wilson The authors review the evidence about the health status of internationally adopted children and describe how these children can transmit disease to members of their adoptive families. They conclude with advice for people who are about to travel abroad to bring an adopted child to his or her new home.
Editorials
Harold C. Sox Hupert and colleagues address the problem of efficient, accurate triage of patients with suspected anthrax. In this commentary, I focus on the article's principal product: a triage algorithm for people who have symptoms of inhalational anthrax.
Thomas A. Glass The articles contained in the supplement to this issue of Annals prompt three questions: What exactly do we mean by successful aging? How does this concept advance our ability to enhance the lives of older adults? What does it mean for clinical practice?
On Being a Doctor
Ruth Lerman It turned out that Dr. Ernst, the medical resident who came to declare my father dead, had known him. I wondered how Dr. Ernst would go through the nonritual of declaring death with us watching, we medical experts, we intimates of my father's heart.
Letters Chronic Hepatitis C Virus Infection
Improved Outcomes in a Voluntary Hospitalist Model
A Nutritional Analysis of an Airline Meal
The Relative Safety of Ephedra Compared with Other Herbal Products
The Churg–Strauss Syndrome after Pranlukast Treatment in a Patient Not Receiving Corticosteroids
Takashi Katsura, Fumihide Yoshida, and Yasutaka Takinishi Correction: Single-Detector Helical Computed Tomography To Diagnose Pulmonary Embolism
Jerome Engel, Jr.
Richard K. Sterling
Ronald L. Koretz This Update reviews several important papers on Barrett esophagus,Helicobacter pylori, hepatology, and inflammatory bowel disease. | ||||||||||||||||||||||||||
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