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Articles 
Bruce P. Barrett, Roger L. Brown, Kristin Locken, Rob Maberry, James A. Bobula, and Donn D'Alessio Compared with placebo, unrefined echinacea provided no detectable benefit or harm in college students who had the common cold.
George Ostapowicz, Robert J. Fontana, Frank V. Schiødt, Anne Larson, Timothy J. Davern, Steven H.B. Han, Timothy M. McCashland, A. Obaid Shakil, J. Eileen Hay, Linda Hynan, Jeffrey S. Crippin, Andres T. Blei, Grace Samuel, Joan Reisch, William M. Lee the U.S. Acute Liver Failure Study Group* Acetaminophen overdose and idiosyncratic drug reactions have replaced viral hepatitis as the most frequent causes of acute liver failure. The cause of liver failure and coma grade at admission were associated with outcome. Although transplantation may improve patient survival, most patients did not need it or could not get it.
Paolo Prandoni, Anthonie W.A. Lensing, Martin H. Prins, Enrico Bernardi, Antonio Marchiori, Paola Bagatella, Michela Frulla, Laura Mosena, Daniela Tormene, Andrea Piccioli, Paolo Simioni, and Antonio Girolami Residual venous thrombosis after discontinuing anticoagulation is an important risk factor for recurrent thromboembolism. Assessing residual venous thrombosis with ultrasonography may help clinicians to identify patients who need prolonged anticoagulation.
Brief Communications
Alfredo Alberti, Franco Noventa, Luisa Benvegnù, Silvia Boccato, and Angelo Gatta Up to 40% of asymptomatic persons with hepatitis C virus infection have histologically active and progressive hepatitis. The severity of liver disease correlates with abnormal alanine aminotransferase levels and increases with age.
Academia and Clinic
David M. Eisenberg, Michael H. Cohen, Andrea Hrbek, Jonathan Grayzel, Maria I. Van Rompay, and Richard A. Cooper This article describes models for health care credentialing of chiropractors, acupuncturists, naturopaths, massage therapists, and other complementary and alternative medical (CAM) practitioners. It also suggests a strategy of CAM provider credentialing for use by physicians, health care administrators, insurance companies, and national professional organizations.
Reviews
Xander H.T. Wehrens, Marc A. Vos, Pieter A. Doevendans, and Hein J.J. Wellens The congenital long QT syndrome is a potentially life-threatening condition caused by mutations in genes encoding cardiac ion channels. The increasing understanding of the mechanisms responsible for these conditions should lead to genotype-specific therapy.
History of Medicine
Michael R. Albert, Kristen G. Ostheimer, David J. Liewehr, Seth M. Steinberg, and Joel G. Breman The authors describe clinical manifestations of smallpox during Boston's last major epidemic (1901–1903) and analyze factors associated with survival among patients admitted to one hospital.
Editorials
Ronald B. Turner The study by Barrett and colleagues in this issue is a valuable contribution to the literature on echinacea because it addresses many shortcomings of earlier studies. Although the study was carefully done and the results are clear, their work is not likely to end the discussion about the efficacy of echinacea for the common cold.
On Being a Doctor
Lucie Opatrny He reached out to grasp my resting hand. Then, suddenly, this man, who had until now spoken and moved so very slowly, started rapidly and vigorously rubbing my hand between both of his. "To warm you up, doctor. My wife also gets cold when she's tired. This has always helped her," Mr. B. explained, never taking his eyes off his task. "You should be sleeping to take care of yourself instead of old men like me," he added.
On Being a Patient
Samuel C. Durso I was struck by the irony of this doctor–patient relationship. In the office our relationship was conventional. He was the heart patient and I was his doctor. The marsh was different. Here Ezra and I were in each other's hands.
Letters Careful Conversation about Care at the End of Life
Reporting Enrollment in Clinical Trials
The Risk–Benefit Profile of Commonly Used Herbal Therapies
Careful Conversation about Care at the End of Life
Physician Involvement in Voluntary Stopping of Eating and Drinking
Reflections on Medical Journals
Use of Antiviral Therapy in Patients with Hepatitis C
Angina Caused by Calcific Constrictive Pericarditis
Foamy Macrophage Syndrome due to Hydroxyethyl Starch Replacement: A Severe Side Effect in Plasmapheresis
Recertification
Jack Coulehan
Jack Coulehan
Bennett Lorber This Update covers terrorist threats to the health of the public, new approaches to some familiar clinical problems, newly recognized disorders, novel treatments for infectious diseases, HIV infection, and infectious complications of treatment for other illnesses. | |||||||||||||||||||||||||||||||||||||||||||||||||||
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