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Articles 
Angelo Scuteri, Angelo J.G. Bos, Larry J. Brant, Laura Talbot, Edward G. Lakatta, and Jerome L. Fleg Postmenopausal women taking hormone replacement therapy have a smaller increase in systolic blood pressure over time than those not taking this therapy. This difference is intensified at older ages.
Janet C. Mohle-Boetani, Jeff A. Farrar, S. Benson Werner, Dzovag Minassian, Ray Bryant, Sharon Abbott, Laurence Slutsker, Duc J. Vugia for the Investigation Team* In California, from 1996 through 1998, more than 50% of multicounty outbreaks with confirmed food vehicles were related to alfalfa or clover sprouts. This summary of the investigations of these outbreaks indicates that sprouts can be a hazardous food. Seed and sprout growers should implement measures to decrease contamination, and the general public should recognize the risks of eating sprouts.
Gabor G. Illei, Howard A. Austin, III, Marianna Crane, Lee Collins, Mark F. Gourley, Cheryl H. Yarboro, Ellen M. Vaughan, Takashi Kuroiwa, Carol L. Danning, Alfred D. Steinberg, John H. Klippel, James E. Balow, and Dimitrios T. Boumpas With extended follow-up, pulse cyclophosphamide continued to show superior efficacy over pulse methylprednisolone alone for treatment of lupus nephritis. The combination of pulse cyclophosphamide and methylprednisolone appears to provide additional benefit over pulse cyclophosphamide alone and does not confer additional risk for adverse events.
Brief Communications
Anna M. Sawka, William F. Young, Jr., Geoffrey B. Thompson, Clive S. Grant, David R. Farley, Cynthia Leibson, and Jon A. van Heerden Resolution of hypertension after adrenalectomy for primary aldosteronism is independently associated with a lack of family history of hypertension and preoperative use of two or fewer antihypertensive agents.
Academia and Clinic
Ronald C. Kessler, Roger B. Davis, David F. Foster, Maria I. Van Rompay, Ellen E. Walters, Sonja A. Wilkey, Ted J. Kaptchuk, and David M. Eisenberg Although recent research has shown that many people in the United States use complementary and alternative medical (CAM) therapies, little is known about time trends in use. These authors found that use of CAM therapies by a large proportion of the study sample is the result of a secular trend that began at least a half-century ago. This trend suggests a continuing demand for CAM therapies that will affect health care delivery for the foreseeable future.
Reviews
Jürgen Westermann, Britta Engelhardt, and Jörg C. Hoffmann The authors review the migration of labeled T-cell subsets in unmanipulated animals, discuss the relevance of these findings to the clinical outcome of anti–adhesion-molecule therapy, and outline how these observations may help us better understand T-cell–mediated diseases and develop new therapeutic strategies.
Editorials
Edmund J. Lewis In this issue, Illei and colleagues report on a clinical trial of lupus nephritis that compared parenteral methylprednisolone, parenteral cyclophosphamide, and a combination of these two treatments, all in addition to low-dose oral prednisone. Their study raised hope that a more definitive answer to ideal therapy is on the horizon. Unfortunately, the study has important limitations.
Letters Sterile Injection Equipment To Prevent HIV Infection
Using Cost-Effectiveness To Target Cholesterol Reduction
The Tragic Events of April 1996
Update in General Internal Medicine
Update in Pulmonary Disease
Comparison of Cardiac Risk Indices
Postprandial Hypotension and Relation to Falls in Institutionalized Elderly Persons
Regarding the Unkind Death of Billie Belle
Novel Presentation of Acute Myelogenous Leukemia as Symptomatic Galactorrhea
Critical Aortic Stenosis with Severe Congestive Heart Failure
Factitious Pheochromocytoma-Like Hypertensive Bouts Caused by the Valsalva Maneuver
Severe Hypersensitivity Associated with Clopidogrel
Hepatocellular Injury in a Patient Receiving Pioglitazone
Do Resistin and Resistin-Like Molecules Also Link Obesity to Inflammatory Diseases?
Death by Diagnosis
Correction: Nonhypoglycemic Effects of Thiazolidinediones
Ana Marusic
Marshall B. Kapp
Aaron Levin
John V.L. Sheffield and Eric B. Larson This year's Update in General Internal Medicine spans a wide area but fits into a framework of the following themes: hypertension, hormone replacement therapy, anticoagulation, atrial fibrillation, chronic infectious diseases, hospital care, and prevention. | ||||||||||||||||||||||||||||||||||||||||||||
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