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Articles 
David R. Gifford, Robert G. Holloway, Martin R. Frankel, Carol L. Albright, Rebecca Meyerson, Robert C. Griggs, and Barbara G. Vickrey Educational methods that encourage physicians to adopt practice guidelines are needed. This study found that a multifaceted education strategy can improve neurologists' adherence to practice recommendations endorsed by specialty societies.
Teresa A. Brentnall, Mary P. Bronner, David R. Byrd, Rodger C. Haggitt, and Michael B. Kimmey Thorough screening of patients with a family history of pancreatic cancer is feasible. Clinical data combined with imaging studies can be used to identify high-risk patients who have dysplasia. The role of molecular genetic testing is uncertain at this time.
Eric A. Engels, Philip S. Rosenberg, Thomas R. O'Brien, James J. Goedert for the Multicenter Hemophilia Cohort Study In patients with hemophilia and late-stage HIV disease, viral load predicts disease progression independently of CD4 cell counts. Because viral load most strongly predicts progression immediately after it is measured, it seems to reflect the current level of immunosuppression.
Brief Communications
Maureen T. Connelly, Nancy Ferrari, Nicole Hagen, and Thomas S. Inui Many women in a managed care organization who accepted a prescription for hormone replacement therapy identified counseling needs that are not included in widely used hormone replacement therapy guidelines.
Marisa A. Montecalvo, William R. Jarvis, Jane Uman, David K. Shay, Coleen Petrullo, Karen Rodney, Cheryl Gedris, Harold W. Horowitz, and Gary P. Wormser Enhanced infection-control strategies reduced transmission of vancomycin-resistant enterococci in an oncology unit in which these organisms were endemic.
Reviews
Ralph A. DeFronzo This review examines the goals of antihyperglycemic therapy and the mechanisms of action, efficacy, nonglycemic benefits, cost, and safety profile of each of the five approved classes of oral agents. A rationale for the use of these agents as monotherapy, in combination with each other, and in combination with insulin is also provided.
Editorials
Jeoffrey K. Stross In this issue, Gifford and colleagues report on an intervention designed to improve adherence to practice guidelines. Despite the study's many strengths, the intervention's effects on physician behavior were not impressive. What factors may explain these findings, and what other methods can be used to change physician behavior?
On Being a Doctor
Nancy L. Greengold What world would I join—full-time physicianhood or health care administration? Did I go through medical school, residency, and fellowship to be a cop? Or is it better to be a cop than a copee?
Letters Update in Endocrinology
Compliance with Handwashing
Epidemiology of Mycobacterium kansasii
Diagnosis of Hemochromatosis
Oral Thymic Extract To Treat Hepatitis C
Fluoroquinolone Resistance in Streptococcus pneumoniae
Reversal of Protease Inhibitor–Related Visceral Abdominal Fat Accumulation with Recombinant Human Growth Hormone
Acute Hepatitis A in Patients with Chronic Hepatitis C
Polyclonal Hyperglobulinemia and Spurious Hypophosphatemia
George E. Ehrlich
Phillip J. Cozzi
Vladimir Hachinski
Aaron Levin
Doris Margolis
Harold W. Horowitz
John G. Bartlett Infectious diseases continues to be one of the fastest-changing fields of clinical medicine. The topics covered in this Update include emergence of antibiotic-resistant organisms, the continuing problems with food-borne disease, and the potential role of certain bacterial infections in coronary heart disease and acute myocardial infarction. | ||||||||||||||||||||||||||||||||||||||||||||
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