Association between Body Mass Index and Diabetes and Hepatocellular Carcinoma

  1. Kazuki Ikeda, MD;
  2. Hiroyuki Marusawa, MD, PhD; and
  3. Tsutomu Chiba, MD, PhD
  1. From Kyoto University, Kyoto, Japan 606-8507.

    IN RESPONSE:

    We thank Drs. Loomba and Ghany for their comments. As they pointed out, obesity is widely recognized as a significant risk factor for many types of human cancer, including HCC (1). In our paper, we prospectively analyzed the various clinical factors, including anti-HBc positivity, smoking, and alcohol intake, as risks for the occurrence of HCC in Japanese patients with hepatitis C virus (HCV) infection.

    We found that the incidence of HCC in …

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