Brief Communication: Severe Hepatotoxicity of Telithromycin: Three Case Reports and Literature Review

Figure 2. A conventional hematoxylin–eosin stain shows only rare islands of surviving regenerative lobular cellularity ( ). (Original magnification, ×5.) Reticulin silver staining demonstrates dense condensation of fibers surrounding persisting ducts without any intervening lobules, except in the regenerative nodule ( ). (Original magnification, × 5.) Immunohistochemical stain for cytokeratin cocktail AE1/AE3 highlights the dense aggregates of ducts ( ) uninterrupted by lobular elements. (Original magnification, ×5.)
Figure 2. A conventional hematoxylin–eosin stain shows only rare islands of surviving regenerative lobular cellularity ( ). (Original magnification, ×5.) Reticulin silver staining demonstrates dense condensation of fibers surrounding persisting ducts without any intervening lobules, except in the regenerative nodule ( ). (Original magnification, × 5.) Immunohistochemical stain for cytokeratin cocktail AE1/AE3 highlights the dense aggregates of ducts ( ) uninterrupted by lobular elements. (Original magnification, ×5.) Microscopic findings for patient 2.Left.arrowMiddle.arrowRight.arrows

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  1. Published online before print February 15, 2006, Ann Intern Med March 21, 2006 vol. 144 no. 6 415-420
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