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Genetic Risk Assessment and BRCA Mutation Testing
- Francois Eisinger, MD; and
- Douglas E. Horsman, MD
- From Paoli Calmettes Institute, 13009 Marseille, France; and British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada.
TO THE EDITOR:
As usual, the U.S. Preventive Services Task Force (USPSTF) carried out an outstanding and comprehensive assessment of health services (1). However, we would like to express 3 concerns. First, should the test really be offered only to women whose family history is associated with an increased risk for deleterious mutations in BRCA1 or BRCA2? We believe that we should consider any criteria—individual or familial—that gives us a clue that a women is at risk for carrying the mutation, and we believe that every woman with the same level of risk should be treated in …
