Cardiac Resynchronization Therapy in Heart Failure

  1. Finlay A. McAlister, MD, MSc;
  2. Natasha Wiebe, Mmath; and
  3. William Abraham, MD
  1. From University of Alberta Hospital, Edmonton, Alberta T6G 2R7, Canada; University of Alberta Campus, Edmonton, Alberta T6G 2J3, Canada; and Ohio State University, Columbus, OH 43210.

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    IN RESPONSE:

    We agree with Drs. Carbajal, Huang, and Hu that several trials included in our systematic review had potential methodologic deficiencies. Although we had space to highlight only 1 of these deficiencies in our published manuscript (randomization after implantation of the CRT device in all but 1 trial), we refer interested readers to our full Agency for Healthcare Research and Quality report, available at http://www.ahrq.gov/clinic/tp/resyntp.htm, for a full …

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