Cost-Effectiveness of Cardiac Resynchronization Therapy in Patients with Symptomatic Heart Failure
- Graham Nichol, MPH, MD;
- Padma Kaul, PhD;
- Ella Huszti, MSc; and
- John F.P. Bridges, PhD
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From University of Washington–Harborview Prehospital Emergency Care Research and Training Center and Harborview Medical Center,
Seattle, Washington; Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada; University of Alberta,
Edmonton, Alberta, Canada; and Case Western Reserve University, Cleveland, Ohio.
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Figure 1. Markov model of medical therapy for heart failure.
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Figure 2. Markov model of cardiac resynchronization therapy (CRT) for heart failure.
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Figure 3. For the base-case point estimate ( ), incremental costs = $30 252 and incremental effect = 0.282 quality-adjusted
life-year ( ). Distribution of incremental costs versus incremental effects for cardiac resynchronization therapy versus medical therapy.white
XQALY
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Appendix Figure. QALY = quality-adjusted life-year. Cost-effectiveness acceptability curve.
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Ann Intern Med
September 7, 2004
vol. 141
no. 5
343-351