Cost-Effectiveness of Cardiac Resynchronization Therapy in Patients with Symptomatic Heart Failure

  1. Graham Nichol, MPH, MD;
  2. Padma Kaul, PhD;
  3. Ella Huszti, MSc; and
  4. John F.P. Bridges, PhD
  1. From University of Washington–Harborview Prehospital Emergency Care Research and Training Center and Harborview Medical Center, Seattle, Washington; Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada; University of Alberta, Edmonton, Alberta, Canada; and Case Western Reserve University, Cleveland, Ohio.
    1. Figure 1.
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      Figure 1. Markov model of medical therapy for heart failure.
    2. Figure 2.
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      Figure 2. Markov model of cardiac resynchronization therapy (CRT) for heart failure.
    3. Figure 3. For the base-case point estimate ( ), incremental costs = $30 252 and incremental effect = 0.282 quality-adjusted life-year ( ).
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      Figure 3. For the base-case point estimate ( ), incremental costs = $30 252 and incremental effect = 0.282 quality-adjusted life-year ( ). Distribution of incremental costs versus incremental effects for cardiac resynchronization therapy versus medical therapy.white XQALY
    4. Appendix Figure. QALY = quality-adjusted life-year.
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      Appendix Figure. QALY = quality-adjusted life-year. Cost-effectiveness acceptability curve.
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