Medical Management of the Acute Radiation Syndrome: Recommendations of the Strategic National Stockpile Radiation Working
Group

Figure 1. Shown are approximate times for hematopoietic, gastrointestinal ( ), and central nervous system ( ) symptoms at
different ranges of dose of whole-body radiation for exposed, living persons. Hematopoietic changes include development of
lymphopenia, granulocytopenia, or thrombocytopenia. Gastrointestinal symptoms include headache, nausea, vomiting, or diarrhea.
Cerebrovascular signs and symptoms include headache, impaired cognition, disorientation, ataxia, seizures, prostration, and
hypotension. Note that the signs and symptoms of different organ systems significantly overlap at each radiation dose and
that cerebrovascular symptoms do not appear until exposure to a high whole-body dose. The relative severity of signs and symptoms
is measured on an arbitrary scale. Prepared from data in reference .
Approximate time course of clinical manifestations.GICNS16
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Ann Intern Med
June 15, 2004
vol. 140
no. 12
1037-1051