Breast Cancer Screening: A Summary of the Evidence for the U.S. Preventive Services Task Force

Appendix (Figure 1). Trials of mammography link screening to health outcomes, but do not address the intermediate steps (screening
and early treatment) or harms (adverse effects of screening and early treatment). Arrows indicating screening and early treatment
represent the intermediate steps in the causal chain linking screening with improved mortality and morbidity.
Analytic framework.
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Ann Intern Med
September 3, 2002
vol. 137
no. 5 Part 1
347-360