Table of Contents

July 16, 2002; 137 (2)

Articles

  • Ciprofloxacin plus Piperacillin Compared with Tobramycin plus Piperacillin as Empirical Therapy in Febrile Neutropenic Patients: A Randomized, Double-Blind Trial

    • James E. Peacock, Jr.,
    • Deirdre A. Herrington,
    • James C. Wade,
    • Hillard M. Lazarus,
    • Michael D. Reed,
    • Jane W. Sinclair,
    • Daniel C. Haverstock,
    • Steven F. Kowalsky,
    • David D. Hurd,
    • Deborah A. Cushing,
    • Colleen P. Harman,
    • and Gerald R. Donowitz
    Ann Intern Med July 16, 2002 137:77-87

    Empirical therapy with an aminoglycoside and a β-lactam remains common for febrile neutropenic patients. Concerns about aminoglycoside-induced ototoxicity and nephrotoxicity have led to studies of alternate regimens. In this study, ciprofloxacin–piperacillin was as safe and effective as tobramycin–piperacillin for empirical therapy of neutropenic fever.

  • Use of the Electrocardiograph-Based Thrombolytic Predictive Instrument To Assist Thrombolytic and Reperfusion Therapy for Acute Myocardial Infarction: A Multicenter, Randomized, Controlled, Clinical Effectiveness Trial

    • Harry P. Selker,
    • Joni R. Beshansky,
    • John L. Griffith,
    • and for the TPI Trial Investigators*
    Ann Intern Med July 16, 2002 137:87-95

    Although its effect was minimal on patients with high baseline reperfusion rates, the electrocardiograph-based Thrombolytic Predictive Instrument increased use and timeliness of reperfusion in often-missed groups and when involved physicians were off site.

  • Cost-Effectiveness Analyses of Colorectal Cancer Screening: A Systematic Review for the U.S. Preventive Services Task Force

    • Michael Pignone,
    • Somnath Saha,
    • Tom Hoerger,
    • and Jeanne Mandelblatt
    Ann Intern Med July 16, 2002 137:96-104

    Screening for colorectal cancer appears cost-effective compared with no screening, but a single optimal strategy cannot be determined from the currently available data. Additional data and additional analyses are necessary.

Brief Communications

  • Safety and Efficacy of Liposomal Amphotericin B Compared with Conventional Amphotericin B for Induction Therapy of Histoplasmosis in Patients with AIDS

    • Philip C. Johnson,
    • L. Joseph Wheat,
    • Gretchen A. Cloud,
    • Mitchell Goldman,
    • Dan Lancaster,
    • David M. Bamberger,
    • William G. Powderly,
    • Richard Hafner,
    • Carol A. Kauffman,
    • William E. Dismukes,
    • and for the U.S. National Institute of Allergy and Infectious Diseases Mycoses Study Group*
    Ann Intern Med July 16, 2002 137:105-109

    In patients with moderate to severe histoplasmosis associated with AIDS, the preferred treatment has been the deoxycholate formulation of amphotericin B. However, serious side effects are associated with this drug. This study found that liposomal amphotericin B was less toxic than amphotericin B and was associated with improved survival.

Academia and Clinic

  • Unexpected Hypoglycemia in a Critically Ill Patient

    • David W. Bates
    Ann Intern Med July 16, 2002 137:110-116

    This article analyzes the case of a patient with iatrogenic hypoglycemia due to administration of the wrong medication. The institution's “root-cause analysis” of the factors contributing to this particular adverse event and the institution's response are discussed, and the literature on preventing medication errors is reviewed.

  • Reforming Care for Persons Near the End of Life: The Promise of Quality Improvement

    • Joanne Lynn,
    • Kevin Nolan,
    • Andrea Kabcenell,
    • David Weissman,
    • Casey Milne,
    • Donald M. Berwick,
    • and for the End-of-Life Care Consensus Panel*
    Ann Intern Med July 16, 2002 137:117-122

    Most people in developed countries will live with a serious, eventually fatal, chronic condition for months or years before dying, yet the delivery of health care services has only recently begun adapting to this reality. Lynn and colleagues discuss a composite case study in a nursing home setting, which builds on experience with multisite collaborative efforts and introduces quality improvement methods in the context of end-of-life care.

Clinical Guidelines

  • Screening for Colorectal Cancer: Recommendation and Rationale

    • U.S. Preventive Services Task Force*
    Ann Intern Med July 16, 2002 137:129-131

    The U.S. Preventive Services Task Force strongly recommends that clinicians routinely provide colorectal cancer screening for all adults 50 years of age or older.

  • Screening for Colorectal Cancer in Adults at Average Risk: A Summary of the Evidence for the U.S. Preventive Services Task Force

    • Michael Pignone,
    • Melissa Rich,
    • Steven M. Teutsch,
    • Alfred O. Berg,
    • and Kathleen N. Lohr
    Ann Intern Med July 16, 2002 137:132-141

    This systematic review supports the U.S. Preventive Services Task Force's position on screening for colorectal cancer.

Editorials

  • Fever, Neutropenia, and the Second Law of Thermodynamics

    • Lindsey R. Baden and
    • Robert H. Rubin
    Ann Intern Med July 16, 2002 137:123-124

    The management of the patient with cancer who has chemotherapy-induced neutropenia and fever has changed markedly over the past four decades. Empirical antimicrobial therapy is now the standard of care for any patient with cancer and neutropenia who has unexplained fever, rigors, or subtler signs of sepsis. The study by Peacock and colleagues in this issue adds significantly to our understanding of the effect of this approach in patients with cancer.

  • Indwelling Urinary Catheters: A One-Point Restraint?

    • Sanjay Saint,
    • Benjamin A. Lipsky,
    • and Susan Dorr Goold
    Ann Intern Med July 16, 2002 137:125-127

    More than four decades ago, Dr. Paul Beeson persuasively argued against routine use of indwelling urinary catheters in hospitalized patients, making the “case against the catheter.” This advice remains relevant today.

On Being a Doctor

  • Doctor's Luck

    • Neil Nakadate
    Ann Intern Med July 16, 2002 137:142

    My father's precise, thorough ways as a fly fisherman told you what to expect of his ways in the practice of anesthesiology.

Letters

  • Physicians and Joint Negotiations

    • Marc Baltzan, Sr.
    Ann Intern Med July 16, 2002 137:143

  • Blue Light and Milk

    • Alice M. Godfrey
    Ann Intern Med July 16, 2002 137:143

  • Fruit and Vegetable Intake and Coronary Heart Disease

    • Alexandra Alves-Rodrigues and
    • Boban Thomas
    Ann Intern Med July 16, 2002 137:143-144

  • Fruit and Vegetable Intake and Coronary Heart Disease

    • Peter Lindenauer,
    • Darius A. Rastegar,
    • and Dorothea von Goeler
    Ann Intern Med July 16, 2002 137:144

  • Fruit and Vegetable Intake and Coronary Heart Disease

    • Kaumudi J. Joshipura,
    • Frank B. Hu,
    • and Walter C. Willett
    Ann Intern Med July 16, 2002 137:144

  • Questioning the Treatment of Venous Thromboembolism

    • David K. Cundiff
    Ann Intern Med July 16, 2002 137:144-145

  • Questioning the Treatment of Venous Thromboembolism

    • Jack Hirsh and
    • Shannon Bates
    Ann Intern Med July 16, 2002 137:145

  • Rapid-Onset Type 1 Diabetes Mellitus without Pancreatic Exocrine Dysfunction

    • Masatoshi Yamazaki and
    • Tatsuhiko Hayashi
    Ann Intern Med July 16, 2002 137:145-146

  • Hepatotoxicity after Prophylaxis with a Nevirapine-Containing Antiretroviral Regimen

    • Stuart Johnson,
    • Juliana Chan,
    • and Charles L. Bennett
    Ann Intern Med July 16, 2002 137:146-147

  • Correction: The Reliability of Medical Record Review for Estimating Adverse Event Rates

    Ann Intern Med July 16, 2002 137:147

Medical Writings: Book Notes

Ad Libitum

Book Listings

Medical Notices

Summaries for Patients

  • Treatment of Fever in Hospitalized Patients with Low White Blood Cell Counts

    Ann Intern Med July 16, 2002 137:I-20

  • A Decision Aid for Recognizing and Treating Heart Attacks Quickly

    Ann Intern Med July 16, 2002 137:I-24

  • Screening for Colorectal Cancer: Recommendations from the United States Preventive Services Task Force

    Ann Intern Med July 16, 2002 137:I-38

  • Treatment of Histoplasmosis in Patients with HIV Infection

    Ann Intern Med July 16, 2002 137:I-54
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This Issue

July 16, 2002; 137 (2)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Clinical Guidelines
  5. Editorials
  6. On Being a Doctor
  7. Letters
  8. Medical Writings: Book Notes
  9. Ad Libitum
  10. Book Listings
  11. Medical Notices
  12. Summaries for Patients

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