Screening for Prostate Cancer: An Update of the Evidence for the U.S. Preventive Services Task Force
- Russell Harris, MD, MPH; and
- Kathleen N. Lohr, PhD
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From University of North Carolina at Chapel Hill, Chapel Hill, and Research Triangle Institute, Research Triangle Park, North
Carolina.
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Figure. The number of cancer cases detected would be smaller after repeated annual screening. * For men in their 50s, = 50;
for men in their 70s, = 270. † For men in their 50s, = 150; for men in their 70s, = 400. ‡ For men in their 50s, = 17; for
men in their 70s, = 90. § For men in their 50s, = 30; for men in their 70s, = 100. ‖For men in their 50s, = 12; for men in
their 70s, = 63. ¶ For men in their 50s, = 21; for men in their 70s, = 70. In all footnotes, numbers are approximate. Estimated yield of screening with prostate-specific antigen (PSA) testing or with PSA testing and digital rectal examination
(DRE).nnnnnnnnnnnn
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Appendix (Figure 1). Arrows represent steps in the chain of logic connecting screening with reduced morbidity or mortality
from prostate cancer. KQ = key question. Analytic framework for screening for prostate cancer.
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Appendix (Figure 2). Direct evidence of screening efficacy. Ecologic studies of screening efficacy. RCT = randomized, controlled
trial. Selection of articles based on key question 1.Top.Bottom.
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Appendix (Figure 3). Arrows represent steps in the chain of logic connecting screening with reduced morbidity or mortality
from prostate cancer. Selection of articles based on key question 2.
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Appendix (Figure 4). Key questions 3 through 6 address health outcomes of treatment; key question 7 addresses harms of treatment.
RCT = randomized, controlled trial. Selection of articles based on key questions 3 through 6 (top) and top question 7 (bottom).
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Appendix 5. Key question 8 addresses costs and cost-effectiveness of screening, and key question 9 deals with the harms of
screening. Selection of articles based on key questions 8 (top) and 9 (bottom).
- Copyright ©2004 by the American College of Physicians
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Ann Intern Med
December 3, 2002
vol. 137
no. 11
917-929