Chemoprevention of Breast Cancer: A Summary of the Evidence for the U.S. Preventive Services Task Force

Appendix (Figure 1). KQ = key question. KQ 1: Do chemopreventive agents reduce mortality from breast cancer? KQ 2: Do chemopreventive
agents reduce the incidence of breast cancer? KQ 3: Do chemopreventive agents have other beneficial effects? KQ 4: Do chemopreventive
agents increase the risk for adverse effects? KQ 5: What are the costs associated with chemoprevention of breast cancer?
Analytical framework.
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Ann Intern Med
July 2, 2002
vol. 137
no. 1
59-69