Postmenopausal Estrogen Replacement and Risk for Venous Thromboembolism
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Figure 1. Odds ratios for thromboembolic events were higher in the first or second year than in subsequent years in all six
studies reporting results by year of use. Risk for venous thromboembolism by year of estrogen use.
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Figure 2. The pooled estimate of venous thromboembolism risk for all 12 studies meeting eligibility criteria was 2.14 (95%
credible interval, 1.64 to 2.81). Numbers above the lines ending in arrows indicate the outer limits of the confidence intervals.
PEPI = Postmenopausal Estrogen/Progestin Interventions trial. Meta-analysis of estrogen studies.
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Appendix Figure. Flowchart diagram of search and selection of articles.
- Copyright ©2004 by the American College of Physicians
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Ann Intern Med
May 7, 2002
vol. 136
no. 9
680-690