Certain renal diseases seen in clinical practice have a rapid course that soon causes irreversible end-stage renal failure
caused by complete structural damage. These diseases, however, are rare. The more common nephropathies progress more slowly
but still evolve to end-stage renal failure. A multimodal approach that centers on reducing or removing all risk factors associated
with renal disease progression may decrease the time to remission for most patients with proteinuric nephropathies.