Table of Contents

March 19, 2002; 136 (6)

Articles

  • Clinical Characteristics and Treatment Outcome of Early Lyme Disease in Patients with Microbiologically Confirmed Erythema Migrans

    • Robert P. Smith,
    • Robert T. Schoen,
    • Daniel W. Rahn,
    • Vijay K. Sikand,
    • John Nowakowski,
    • Dennis L. Parenti,
    • Mary S. Holman,
    • David H. Persing,
    • and Allen C. Steere
    Ann Intern Med March 19, 2002 136:421-428

    In major endemic areas in the United States, Lyme disease commonly presents as erythema migrans with homogeneous or central redness and nonspecific flu-like symptoms. Clinical outcome is excellent if antibiotic therapy is administered soon after symptom onset.

  • Efficacy of Resident Training in Smoking Cessation: A Randomized, Controlled Trial of a Program Based on Application of Behavioral Theory and Practice with Standardized Patients

    • Jacques Cornuz,
    • Jean-Paul Humair,
    • Laurence Seematter,
    • Rebecca Stoianov,
    • Guy van Melle,
    • Hans Stalder,
    • and Alain Pécoud
    Ann Intern Med March 19, 2002 136:429-437

    A smoking cessation training program that was based on behavioral theory and practice with standardized patients significantly increased the quality of physicians' counseling, smokers' motivation to quit, and rates of smoking abstinence at 1 year.

  • J-Shaped Relationship between Blood Pressure and Mortality in Hypertensive Patients: New Insights from a Meta-Analysis of Individual-Patient Data

    • Florent Boutitie,
    • François Gueyffier,
    • Stuart Pocock,
    • Robert Fagard,
    • Jean Pierre Boissel,
    • and for the INDANA Project Steering Committee
    Ann Intern Med March 19, 2002 136:438-448

    Several studies in hypertensive patients receiving treatment have described the relationship between blood pressure and mortality as J-shaped, with an increased risk for events in patients with low blood pressure. This study found that the increased risk for events in patients with low blood pressure was not related to antihypertensive treatment and was not specific to blood pressure–related events. Poor health conditions leading to low blood pressure and an increased risk for death probably explain the J-shaped curve.

Brief Communications

  • Mixed Hepatocellular–Cholestatic Liver Injury after Pioglitazone Therapy

    • Louis D. May,
    • Jay H. Lefkowitch,
    • Michael T. Kram,
    • and David E. Rubin
    Ann Intern Med March 19, 2002 136:449-452

    As suggested by the patient described in this report, patients receiving pioglitazone may develop serious liver injury and should be observed for evidence of hepatitis.

Review

  • Long-Term Medical Care of Testicular Cancer Survivors

    • David J. Vaughn,
    • Gretchen A. Gignac,
    • and Anna T. Meadows
    Ann Intern Med March 19, 2002 136:463-470

    This case-based discussion focuses on the primary care physician's evaluation and management of a long-term survivor of testicular cancer who was previously treated with surgery and chemotherapy.

Perspectives

  • Deconstructing the Placebo Effect and Finding the Meaning Response

    • Daniel E. Moerman and
    • Wayne B. Jonas
    Ann Intern Med March 19, 2002 136:471-476

    The authors provide a new perspective with which to understand what for a half-century has been known as the “placebo effect.” As currently used, the concept includes much that has nothing to do with placebos, confusing the most interesting and important aspects of the phenomenon. The authors propose a new way to understand those aspects of medical care, plus a broad range of additional human experiences, by focusing on the idea of “meaning,” to which sick people often respond.

Editorials

  • Recognition and Treatment of Erythema Migrans: Are We Off Target?

    • Robert B. Nadelman and
    • Gary P. Wormser
    Ann Intern Med March 19, 2002 136:477-479

    In this issue, Smith and colleagues describe the clinical manifestations of illness and outcome in a group of U.S. patients with erythema migrans and laboratory evidence of Borrelia burgdorferi infection. Their findings suggest that objective review of the information from clinical studies should change the way we think about diagnosing and treating early Lyme disease.

  • “Did This Drug Cause My Patient's Hepatitis?” and Related Questions

    • David W. Nierenberg
    Ann Intern Med March 19, 2002 136:480-483

    What should the busy internist do when his or her patient, while taking several medications, suddenly develops a new clinical problem, such as hepatitis? Is the acute hepatitis drug related? If so, which drug is to blame? In this issue, May and colleagues discuss liver injury attributed to use of pioglitazone.

On Being a Doctor

  • An Examination of Conscience

    • Munsey S. Wheby
    Ann Intern Med March 19, 2002 136:486-487

    Petty illness, trifling fever, transient myalgias had led me to something more: a desperate need to hold on to that something that is the very essence of doctoring.

On Being a Patient

  • On Growing Old

    • Myrtle Lundberg
    Ann Intern Med March 19, 2002 136:484-485

    What happened to that skinny kid—the one so skinny her ribs could be counted just by looking? Today, she is a twittery, purse-clutching, cane-wielding, pill-popping little old lady living alone.

Letters

  • Caring for Patients at the End of Life

    • Peter D. Eisenberg
    Ann Intern Med March 19, 2002 136:W1

  • Diagnosing Primary HIV Infection

    • Christopher D. Pilcher,
    • David Alain Wohl,
    • and Charles B. Hicks
    Ann Intern Med March 19, 2002 136:488

  • Diagnosing Primary HIV Infection

    • Eric S. Daar and
    • Susan Little
    Ann Intern Med March 19, 2002 136:488-489

  • Regression and Progression of Valvulopathy Associated with Fenfluramine and Phentermine

    • Charles F. Dahl and
    • Marvin R. Allen
    Ann Intern Med March 19, 2002 136:489

  • Appropriate Use of Antibiotics: Pharyngitis

    • Alan L. Bisno and
    • Edward L. Kaplan
    Ann Intern Med March 19, 2002 136:489-490

  • Sleep Apnea and Gastroesophageal Reflux Disease

    • Sheldon M. Wolf and
    • Yury Furman
    Ann Intern Med March 19, 2002 136:490-491

  • A Rollover Epidemic in North Dakota from 1994 to 1997

    • Vinod K. Seth
    Ann Intern Med March 19, 2002 136:491

Medical Writings: Book Notes

  • Practical Neuro-Oncology: A Guide to Patient Care

    • Amy A. Pruitt
    Ann Intern Med March 19, 2002 136:492

  • Field Guide to Urgent and Ambulatory Care Procedures

    • Jerrold B. Leikin
    Ann Intern Med March 19, 2002 136:492

Book Listings

Medical Notices

Summaries for Patients

  • Rashes and Symptoms in Early Lyme Disease

    Ann Intern Med March 19, 2002 136:I24

  • Effect of a Training Program for Resident Physicians in Improving Success Rate in Helping Patients Quit Smoking

    Ann Intern Med March 19, 2002 136:I31

  • Relationship between Blood Pressure and Death among Treated Hypertensive Patients at the High and Low Ends of Blood Pressure Control

    Ann Intern Med March 19, 2002 136:I49

  • Liver Damage in a Person Taking the Diabetes Drug Pioglitazone

    Ann Intern Med March 19, 2002 136:I65

Updates from the Annual Session

  • Update in Women's Health

    • Nancy C. Dolan,
    • Karen Freund,
    • and Judith Walsh
    Ann Intern Med March 19, 2002 136:453-462

    This Update discusses issues affecting women of reproductive age, breast cancer treatment, hormone replacement therapy, osteoporosis, cancer screening, and sexual dysfunction.

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This Issue

March 19, 2002; 136 (6)
  1. Articles
  2. Brief Communications
  3. Review
  4. Perspectives
  5. Editorials
  6. On Being a Doctor
  7. On Being a Patient
  8. Letters
  9. Medical Writings: Book Notes
  10. Book Listings
  11. Medical Notices
  12. Summaries for Patients
  13. Updates from the Annual Session

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