Table of Contents

January 1, 2002; 136 (1)

Articles

  • Low-Dose Prednisone Therapy for Patients with Early Active Rheumatoid Arthritis: Clinical Efficacy, Disease-Modifying Properties, and Side Effects: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    • Amalia A. van Everdingen,
    • Johannes W.G. Jacobs,
    • Dirk R. Siewertsz van Reesema,
    • and Johannes W.J. Bijlsma
    Ann Intern Med January 1, 2002 136:1-12

    Prednisone, 10 mg/d, provides clinical benefit, particularly in the first 6 months, and substantially inhibits progression of radiologic joint damage in patients with early active rheumatoid arthritis and no previous treatment with disease-modifying antirheumatic drugs. Because of their limited disease-modifying effects, glucocorticoids should be combined with disease-modifying antirheumatic drugs in patients with rheumatoid arthritis.

  • Risk Factors for Helicobacter pylori Resistance in the United States: The Surveillance of H. pylori Antimicrobial Resistance Partnership (SHARP) Study, 1993–1999

    • Joette M. Meyer,
    • Nancy P. Silliman,
    • Wenjin Wang,
    • Nancy Y. Siepman,
    • Jennifer E. Sugg,
    • David Morris,
    • Jie Zhang,
    • Helen Bhattacharyya,
    • Eileen C. King,
    • and Robert J. Hopkins
    Ann Intern Med January 1, 2002 136:13-24

    Clinicians should consider risk factors for antimicrobial resistance when deciding which patients should have susceptibility testing and when choosing appropriate Helicobacter pylori treatments in the empirical setting.

  • Recovery Rate and Prognosis in Older Persons Who Develop Acute Lung Injury and the Acute Respiratory Distress Syndrome

    • E. Wesley Ely,
    • Arthur P. Wheeler,
    • B. Taylor Thompson,
    • Marek Ancukiewicz,
    • Kenneth P. Steinberg,
    • Gordon R. Bernard,
    • and for the Acute Respiratory Distress Syndrome Network
    Ann Intern Med January 1, 2002 136:25-36

    Although the survival rate among mechanically ventilated patients 70 years of age or older in this study was high, these patients were twice as likely to die of acute lung injury compared with their younger counterparts, even after adjustment for covariates. Older survivors recovered from respiratory failure and achieved spontaneous breathing at the same rate as younger patients but had greater difficulty being liberated from the ventilator and being discharged from the intensive care unit.

Brief Communications

  • Anomalies of the Inferior Vena Cava in Patients with Iliac Venous Thrombosis

    • Andrea Obernosterer,
    • Manuela Aschauer,
    • Wolfgang Schnedl,
    • and Rainer W. Lipp
    Ann Intern Med January 1, 2002 136:37-41

    An anomaly of the inferior vena cava should be suspected if thrombosis involving the iliac veins occurs in patients 30 years of age or younger. Patients with an anomaly and thrombosis may be at higher risk for thrombotic recurrence.

Academia and Clinic

  • The Risk–Benefit Profile of Commonly Used Herbal Therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava

    • Edzard Ernst
    Ann Intern Med January 1, 2002 136:42-53

    The author outlines risk–benefit profiles for the most commonly used herbal medicines. These profiles are based on systematic reviews where possible.

Review

  • Therapeutic Angiogenesis for Coronary Artery Disease

    • Saul Benedict Freedman and
    • Jeffrey M. Isner
    Ann Intern Med January 1, 2002 136:54-71

    This review discusses the biology of angiogenesis that forms the basis for clinical studies of patients with coronary artery disease, and it summarizes information from clinical trials of therapeutic angiogenesis for myocardial ischemia.

Perspectives

  • Caring for Patients at the End of Life: Reflections after 12 Years of Practice

    • Richard A. Parker
    Ann Intern Med January 1, 2002 136:72-75

    The author describes interactions with families of dying patients, discusses logistic issues around dying, examines do-not-resuscitate orders, and highlights experiences with home visits.

Position Papers

  • Pharmacist Scope of Practice

    • American College of Physicians–American Society of Internal Medicine*
    Ann Intern Med January 1, 2002 136:79-85

    This paper explores the increased scope of practice of U.S. pharmacists, presents background information on the pharmacy profession, and outlines how the medical profession can work with pharmacists to enhance patient safety and quality of care.

Editorial

  • Are Long-Term Very Low Doses of Prednisone for Patients with Rheumatoid Arthritis as Helpful as High Doses Are Harmful?

    • Theodore Pincus,
    • Tuulikki Sokka,
    • and C. Michael Stein
    Ann Intern Med January 1, 2002 136:76-78

    The elegantly designed and well-executed study by van Everdingen and colleagues in this issue presents a unique opportunity to evaluate benefits and risks of corticosteroid therapy for rheumatoid arthritis independent of other therapies; this clinical setting is unlikely to recur. It is commendable that these authors chose to reanalyze a therapy that has been available for more than 50 years.

Letters

Book Listings

Medical Notices

Summaries for Patients

  • Factors Associated with Helicobacter pylori Infections in the United States That Are Resistant to Usual Antibiotics

    Ann Intern Med January 1, 2002 136:S67

  • Recovery Rate and Prognosis in Older Persons Who Develop Acute Lung Injury and the Acute Respiratory Distress Syndrome

    Ann Intern Med January 1, 2002 136:S68

  • Blood Clots and Abnormal Vessels of the Inferior Vena Cava

    Ann Intern Med January 1, 2002 136:S69

  • Prednisone for Rheumatoid Arthritis

    Ann Intern Med January 1, 2002 136:S72
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This Issue

January 1, 2002; 136 (1)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Review
  5. Perspectives
  6. Position Papers
  7. Editorial
  8. Letters
  9. Book Listings
  10. Medical Notices
  11. Summaries for Patients

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