Table of Contents

November 6, 2001; 135 (9)

Articles

  • Serologic and Clinical Outcomes of 1536 Alaska Natives Chronically Infected with Hepatitis B Virus

    • Brian J. McMahon,
    • Peter Holck,
    • Lisa Bulkow,
    • and Mary Snowball
    Ann Intern Med November 6, 2001 135:759-768

    Hepatitis B e antigen cleared in more than 70% of 1536 Alaska Native patients positive for hepatitis B surface antigen during the first 10 years of follow-up.

  • Aspirin as an Adjunct to Screening for Prevention of Sporadic Colorectal Cancer: A Cost-Effectiveness Analysis

    • Uri Ladabaum,
    • Cathy Lee Chopra,
    • Grace Huang,
    • James M. Scheiman,
    • Michael E. Chernew,
    • and A. Mark Fendrick
    Ann Intern Med November 6, 2001 135:769-781

    In patients undergoing colorectal cancer screening, aspirin use should not be based on potential chemoprevention. Aspirin chemoprophylaxis alone cannot be considered a substitute for colorectal cancer screening. Public policy should focus on improving screening adherence, even in patients who are already taking aspirin.

  • Effects of CCR5-Δ 32, CCR2-64I, and SDF-1 3′A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data

    • John P.A. Ioannidis,
    • Philip S. Rosenberg,
    • James J. Goedert,
    • Lesley J. Ashton,
    • Thomas L. Benfield,
    • Susan P. Buchbinder,
    • Roel A. Coutinho,
    • Jesper Eugen-Olsen,
    • Teresa Gallart,
    • Terese L. Katzenstein,
    • Leondios G. Kostrikis,
    • Harmjan Kuipers,
    • Leslie G. Louie,
    • Simon A. Mallal,
    • Joseph B. Margolick,
    • Olga P. Martinez,
    • Laurence Meyer,
    • Nelson L. Michael,
    • Eva Operskalski,
    • Giusseppe Pantaleo,
    • G. Paolo Rizzardi,
    • Hanneke Schuitemaker,
    • Haynes W. Sheppard,
    • Graeme J. Stewart,
    • Ioannis D. Theodorou,
    • Henrik Ullum,
    • Elisa Vicenzi,
    • David Vlahov,
    • David Wilkinson,
    • Cassy Workman,
    • Jean-Francois Zagury,
    • Thomas R. O'Brien,
    • and for the International Meta-Analysis of HIV Host Genetics
    Ann Intern Med November 6, 2001 135:782-795

    The CCR5-Δ 32 and CCR2-64I alleles had a strong protective effect on progression of HIV-1 infection, but SDF-1 3`A homozygosity carried no such protection.

Brief Communications

  • Hepatitis B Virus Infection in Children and Adolescents in a Hyperendemic Area: 15 Years after Mass Hepatitis B Vaccination

    • Yen-Hsuan Ni,
    • Mei-Hwei Chang,
    • Li-Min Huang,
    • Huey-Ling Chen,
    • Hong-Yuan Hsu,
    • Tai-Yuan Chiu,
    • Keh-Sung Tsai,
    • and Ding-Shinn Chen
    Ann Intern Med November 6, 2001 135:796-800

    Universal vaccination in Taiwan significantly decreased the hepatitis B virus (HBV) carrier rate and infection rate among children and adolescents born since the program began in 1984. By decreasing the carrier pool, continuation of the national hepatitis B immunization program should prevent HBV infection in the children of Taiwan and, subsequently, adults as well.

Reviews

  • Unrecognized Myocardial Infarction

    • Stuart E. Sheifer,
    • Teri A. Manolio,
    • and Bernard J. Gersh
    Ann Intern Med November 6, 2001 135:801-811

    This review of myocardial infarctions that escape clinical recognition focuses on the prevalence, predisposing factors, and prognosis, and incorporates data from relevant epidemiologic studies, basic science investigations, and review articles.

  • Ventricular Septal Defects in Adults

    • Naser M. Ammash and
    • Carole A. Warnes
    Ann Intern Med November 6, 2001 135:812-824

    Because congenital ventricular septal defects are of different sizes and locations, their clinical presentation, natural history, and treatment vary greatly. This review discusses the different types of ventricular septal defects commonly seen in adults.

Perspectives

  • Clinical Inertia

    • Lawrence S. Phillips,
    • William T. Branch, Jr.,
    • Curtiss B. Cook,
    • Joyce P. Doyle,
    • Imad M. El-Kebbi,
    • Daniel L. Gallina,
    • Christopher D. Miller,
    • David C. Ziemer,
    • and Catherine S. Barnes
    Ann Intern Med November 6, 2001 135:825-834

    Medicine has traditionally focused on relieving patient symptoms. However, in developed countries, maintaining good health increasingly involves management of such problems as hypertension, dyslipidemia, and diabetes, which often have no symptoms. Limitations in managing such problems are often due to clinical inertia—failure of health care providers to initiate or intensify therapy when indicated.

Editorial

  • Protecting Future Generations through Immunization against Hepatitis B

    • Miriam J. Alter
    Ann Intern Med November 6, 2001 135:835-836

    As suggested by the papers by McMahon and Ni and coworkers in this issue, expanding the cohorts of children immunized as infants and decreasing the number of hepatitis B e antigen–positive persons will ensure that future generations are protected from hepatitis B virus infection and its consequences. However, without a nationwide program to vaccinate adults at increased risk for this infection, acute disease will continue to occur and transmission of hepatitis B virus will not be eliminated for decades.

On Being a Doctor

  • Short Takes

    • John W. Burnside
    Ann Intern Med November 6, 2001 135:837-838

    A physician muses on various aspects of modern clinical practice.

Letters

  • Uncomplicated Acute Bronchitis

    • Ulrich Heininger
    Ann Intern Med November 6, 2001 135:839

  • Uncomplicated Acute Bronchitis

    • Ralph Gonzales and
    • Merle A. Sande
    Ann Intern Med November 6, 2001 135:839-840

  • HIV-1 Protease Inhibitors May Interfere with the Ubiquitous Intracellular Proteases

    • Fehmida Visnegarwala,
    • Daniel M. Musher,
    • and A.C. White, Jr.
    Ann Intern Med November 6, 2001 135:840

  • Fenfluramine and Phentermine

    • Diane Howlin
    Ann Intern Med November 6, 2001 135:840-841

  • Patients with Alcohol Problems

    • Haralampos J. Milionis and
    • Moses S. Elisaf
    Ann Intern Med November 6, 2001 135:841

  • Patients with Alcohol Problems

    • David A. Fiellin,
    • M. Carrington Reid,
    • and Patrick G. O'Connor
    Ann Intern Med November 6, 2001 135:841

  • Prolongation of the QT Interval and Ventricular Tachycardia in Patients Treated with Arsenic Trioxide for Acute Promyelocytic Leukemia

    • Jean T. Barbey and
    • Steven Soignet
    Ann Intern Med November 6, 2001 135:842

  • Prolongation of the QT Interval and Ventricular Tachycardia in Patients Treated with Arsenic Trioxide for Acute Promyelocytic Leukemia

    • Kazunori Ohnishi,
    • Hiroshi Satoh,
    • and Ryuzo Ohno
    Ann Intern Med November 6, 2001 135:842-843

  • Cocaine-Related Vasculitis Causing Upper-Limb Peripheral Vascular Disease

    • John A. Spittell, Jr. and
    • Peter C. Spittell
    Ann Intern Med November 6, 2001 135:843

  • Cocaine-Related Vasculitis Causing Upper-Limb Peripheral Vascular Disease

    • P. Dileep Kumar and
    • Howard R. Smith
    Ann Intern Med November 6, 2001 135:843

  • Regional Osteoporosis in Anorexia Nervosa

    • Philip S. Mehler
    Ann Intern Med November 6, 2001 135:843-844

  • Regional Osteoporosis in Anorexia Nervosa

    • Steven Grinspoon and
    • Anne Klibanski
    Ann Intern Med November 6, 2001 135:844

  • Treatment of Refractory Erdheim–Chester Disease with Double Autologous Hematopoietic Stem-Cell Transplantation

    • Nicolas Boissel,
    • Bertrand Wechsler,
    • and Véronique Leblond
    Ann Intern Med November 6, 2001 135:844-845

Medical Writings: Book Notes

Book Listings

Medical Notices

Summaries for Patients

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This Issue

November 6, 2001; 135 (9)
  1. Articles
  2. Brief Communications
  3. Reviews
  4. Perspectives
  5. Editorial
  6. On Being a Doctor
  7. Letters
  8. Medical Writings: Book Notes
  9. Book Listings
  10. Medical Notices
  11. Summaries for Patients

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