Table of Contents

August 15, 2000; 133 (4)

Articles

  • Duration of Symptoms and Plasma Cytokine Levels in Patients with the Common Cold Treated with Zinc Acetate: A Randomized, Double-Blind, Placebo-Controlled Trial

    • Ananda S. Prasad,
    • James T. Fitzgerald,
    • Bin Bao,
    • Frances W.J. Beck,
    • and Pranatharthi H. Chandrasekar
    Ann Intern Med August 15, 2000 133:245-252

    Use of zinc lozenges was associated with reduced duration and severity of cold symptoms, especially cough. Improvement in clinical symptoms with zinc treatment may be related to a decrease in proinflammatory cytokine levels; in this study, however, the observed changes in cytokine levels did not significantly differ between zinc and placebo groups.

  • Effect of a Preoperative Intervention on Preoperative and Postoperative Outcomes in Low-Risk Patients Awaiting Elective Coronary Artery Bypass Graft Surgery: A Randomized, Controlled Trial

    • Heather M. Arthur,
    • Charlotte Daniels,
    • Robert McKelvie,
    • Jack Hirsh,
    • and Bonnie Rush
    Ann Intern Med August 15, 2000 133:253-262

    The waiting period for elective procedures, such as coronary artery bypass grafting, may be used to enhance in-hospital and early-phase recovery, improving patients' functional abilities and quality of life while reducing their hospital stay.

  • Efficacy and Safety of Troglitazone in the Treatment of Lipodystrophy Syndromes

    • Elif Arioglu,
    • Jennifer Duncan-Morin,
    • Nancy Sebring,
    • Kristina I. Rother,
    • Nicole Gottlieb,
    • Jay Lieberman,
    • David Herion,
    • David E. Kleiner,
    • James Reynolds,
    • Ahalya Premkumar,
    • Anne E. Sumner,
    • Jay Hoofnagle,
    • Marc L. Reitman,
    • and Simeon I. Taylor
    Ann Intern Med August 15, 2000 133:263-274

    Troglitazone therapy improved metabolic control and increased body fat in patients with lipoatrophic diabetes. The substantial benefits of troglitazone must be balanced against the risk for hepatotoxicity, which can occur relatively late in the treatment course.

Brief Communications

  • Anti-CD20 Chimeric Monoclonal Antibody Treatment of Refractory Immune-Mediated Thrombocytopenia in a Patient with Chronic Graft-versus-Host Disease

    • Voravit Ratanatharathorn,
    • Erik Carson,
    • Christopher Reynolds,
    • Lois J. Ayash,
    • John Levine,
    • Gregory Yanik,
    • Samuel M. Silver,
    • James L.M. Ferrara,
    • and Joseph P. Uberti
    Ann Intern Med August 15, 2000 133:275-279

    The efficacy of rituximab for immune-mediated thrombocytopenia in the patient described here suggests that this drug may have activity in other autoimmune diseases or chronic graft-versus-host disease.

  • Effect of Antiretroviral Therapy on HIV Shedding in Semen

    • Paulo F. Barroso,
    • Mauro Schechter,
    • Phalguni Gupta,
    • Maria F. Melo,
    • Marcello Vieira,
    • Fernanda C. Murta,
    • Yeda Souza,
    • and Lee H. Harrison
    Ann Intern Med August 15, 2000 133:280-284

    Antiretroviral therapy reduces shedding of HIV in semen; in turn, this reduction probably decreases HIV transmissibility. However, a substantial proportion of patients may still be infectious and may harbor drug-resistant strains of the virus.

In the Balance

  • The Department of Internal Medicine: Hub of the Academic Health Center Response to the Aging Imperative

    • William R. Hazzard
    Ann Intern Med August 15, 2000 133:293-296

    Given the progressive aging of the U.S. population, it may seem natural for geriatrics to become a separate specialty with its own academic department. The author recommends an alternative—a center on aging or pan-institutional program that is firmly anchored in the department of internal medicine.

  • In Defense of a Department of Geriatrics

    • Christine K. Cassel
    Ann Intern Med August 15, 2000 133:297-301

    The author argues the case for departments of geriatric medicine as institutional structures that can advance research, improve teaching, and enhance patient care.

Editorials

  • Lessons Learned from Attempts To Establish the Blind in Placebo-Controlled Trials of Zinc for the Common Cold

    • Norman A. Desbiens
    Ann Intern Med August 15, 2000 133:302-303

    Prasad and colleagues' study in this issue points to an important, often overlooked issue in randomized, double-blind, placebo-controlled trials: testing the participants' assessment of whether they are receiving placebo or active drug.

  • Lipoatrophy, Lipodystrophy, and Insulin Resistance

    • Om P. Ganda
    Ann Intern Med August 15, 2000 133:304-306

    In this issue, Arioglu and colleagues report that troglitazone led to better metabolic control and increased body fat in patients with lipoatrophic diabetes. What are the mechanisms of the efficacy of troglitazone in these patients?

Letters

  • Economic Sanctions and Embargoes

    • Michael Brumage
    Ann Intern Med August 15, 2000 133:308

  • Economic Sanctions and Embargoes

    • Ken Freeland
    Ann Intern Med August 15, 2000 133:308

  • Economic Sanctions and Embargoes

    • David P. Hickey
    Ann Intern Med August 15, 2000 133:308-309

  • Economic Sanctions and Embargoes

    • Leila Richards
    Ann Intern Med August 15, 2000 133:309

  • Economic Sanctions and Embargoes

    • Soheir A. Morsy
    Ann Intern Med August 15, 2000 133:309-310

  • Economic Sanctions and Embargoes

    • Anthony F. Kirkpatrick
    Ann Intern Med August 15, 2000 133:310

  • Economic Sanctions and Embargoes

    • Richard Garfield
    Ann Intern Med August 15, 2000 133:310-311

  • Economic Sanctions and Embargoes

    • Natalia Ganson-Myshkin
    Ann Intern Med August 15, 2000 133:311

  • Economic Sanctions and Embargoes

    • Michèle Barry
    Ann Intern Med August 15, 2000 133:311-312

  • Histologic Improvement of Fibrosis in Patients with Hepatitis C and Sustained Response to Interferon Therapy

    • Javier Bolaños-Meade and
    • Carmen López-Arvizu
    Ann Intern Med August 15, 2000 133:312

  • Radiofrequency Ablation of Metastatic Lesions in Adrenocortical Cancer

    • Jame Abraham,
    • Tito Fojo,
    • and Bradford J. Wood
    Ann Intern Med August 15, 2000 133:312-313

  • The Pet Separation Syndrome

    • John F. Burnum
    Ann Intern Med August 15, 2000 133:313-314

  • Tobacco Awareness Curricula in Medical Schools

    • Arthur E. Pitchenik,
    • Mark O'Connell,
    • and Donna Wiener
    Ann Intern Med August 15, 2000 133:314

  • Laryngopharyngeal Examination: An Important but Not-So-New Role of Upper Gastrointestinal Endoscopy

    • Joseph Carl Yarze,
    • Michael P. Chase,
    • and Kevin J. Herlihy
    Ann Intern Med August 15, 2000 133:314-315

  • Glutaraldehyde Colitis: A Complication of Screening Flexible Sigmoidoscopy in the Primary Care Setting

    • Karl Fukunaga and
    • Afshin Khatibi
    Ann Intern Med August 15, 2000 133:315

Medical Writings: Book Notes

Current Clinical Issues

  • The Effect of Clinical Practice Guidelines on Variations in Care

    • Linda Gundersen
    Ann Intern Med August 15, 2000 133:317

  • Vitamin D

    • Deborah Gesensway
    Ann Intern Med August 15, 2000 133:318

Ad Libitum

Book Listings

  • Book Listings

    Ann Intern Med August 15, 2000 133:0

Medical Notices

Summaries for Patients

  • Zinc Acetate Lozenges To Treat the Common Cold

    Ann Intern Med August 15, 2000 133:245

  • A Preoperative Program for Patients Awaiting Coronary Artery Bypass Graft (CABG) Surgery

    Ann Intern Med August 15, 2000 133:253

  • Using Troglitazone To Treat People with Lipoatrophy Syndromes

    Ann Intern Med August 15, 2000 133:263

  • Rituximab Treatment of Low Platelet Counts in a Patient with Chronic Graft-versus-Host Disease

    Ann Intern Med August 15, 2000 133:275

  • The Effect of Anti-HIV Drugs on the Amount of HIV in Semen

    Ann Intern Med August 15, 2000 133:280

Updates from the Annual Session

  • Update in Infectious Diseases

    • John G. Bartlett
    Ann Intern Med August 15, 2000 133:285-292

    Topics covered in this Update include antimicrobial resistance, community-acquired pneumonia, and HIV infection.

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This Issue

August 15, 2000; 133 (4)
  1. Articles
  2. Brief Communications
  3. In the Balance
  4. Editorials
  5. Letters
  6. Medical Writings: Book Notes
  7. Current Clinical Issues
  8. Ad Libitum
  9. Book Listings
  10. Medical Notices
  11. Summaries for Patients
  12. Updates from the Annual Session

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