Pathogenesis, Natural History, Treatment, and Prevention of Hepatitis C

Figure 2. Although the hepatocyte is depicted as the target cell of hepatitis C virus ( )-specific immune response here, other
cells, including dendritic cells and macrophages, are also important in antigen presentation to the immune system. CTL = cytotoxic
T cell; IL = interleukin; MHC = major histocompatibility complex; TCR = T-cell receptor; Th = T helper; Th1 = helper T cells
with a type 1 cytokine profile; Th2 = helper T cells with a type 2 cytokine profile; TNF = tumor necrosis factor.
Components of the antiviral immune response.HCV
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Ann Intern Med
February 15, 2000
vol. 132
no. 4
296-305