Table of Contents

September 7, 1999; 131 (5)

Articles

  • Nonfasting Plasma Total Homocysteine Level and Mortality in Middle-Aged and Elderly Men and Women in Jerusalem

    • Jeremy D. Kark,
    • Jacob Selhub,
    • Bella Adler,
    • Jaime Gofin,
    • Joseph H. Abramson,
    • Gideon Friedman,
    • and Irwin H. Rosenberg
    Ann Intern Med September 7, 1999 131:321-330

    A mildly to moderately elevated nonfasting total homocysteine level is a substantial risk marker for death from any cause. The association seems to be stronger during the first 5 years of follow-up.

  • Serum Total Homocysteine Concentrations in the Third National Health and Nutrition Examination Survey (1991–1994): Population Reference Ranges and Contribution of Vitamin Status to High Serum Concentrations

    • Jacob Selhub,
    • Paul F. Jacques,
    • Irwin H. Rosenberg,
    • Gail Rogers,
    • Barbara A. Bowman,
    • Elaine W. Gunter,
    • Jacqueline D. Wright,
    • and Clifford L. Johnson
    Ann Intern Med September 7, 1999 131:331-339

    Upper reference limits for serum total homocysteine concentration increased with age and were higher for male participants than for female participants at all ages. In most cases, high homocysteine concentrations were associated with low serum vitamin levels.

  • Prospective Evaluation of Risk Factors for Bloodstream Infection in Patients Receiving Home Infusion Therapy

    • Jerome I. Tokars,
    • Susan T. Cookson,
    • Margaret A. McArthur,
    • Cindy L. Boyer,
    • Allison J. McGeer,
    • and William R. Jarvis
    Ann Intern Med September 7, 1999 131:340-347

    Bloodstream infections seem to be infrequent among outpatients receiving infusions through central and midline catheters. However, the rate of infection increases with bone marrow transplantation, parenteral nutrition, infusion therapy in a hospital clinic or physician's office, and use of multilumen catheters.

Brief Communications

  • Normalization of Hyperhomocysteinemia with L-thyroxine in Hypothyroidism

    • Wiam I. Hussein,
    • Ralph Green,
    • Donald W. Jacobsen,
    • and Charles Faiman
    Ann Intern Med September 7, 1999 131:348-351

    Hypothyroidism may be a treatable cause of hyperhomocysteinemia, and elevated plasma homocysteine levels may be an independent risk factor for the accelerated atherosclerosis seen in primary hypothyroidism.

  • Nonfasting Plasma Total Homocysteine Levels and Stroke Incidence in Elderly Persons: The Framingham Study

    • Andrew G. Bostom,
    • Irwin H. Rosenberg,
    • Halit Silbershatz,
    • Paul F. Jacques,
    • Jacob Selhub,
    • Ralph B. D'Agostino,
    • Peter W.F. Wilson,
    • and Philip A. Wolf
    Ann Intern Med September 7, 1999 131:352-355

    Nonfasting total homocysteine levels are an independent risk factor for incident stroke in elderly persons.

Reviews

  • Homocyst(e)ine and Cardiovascular Disease: A Critical Review of the Epidemiologic Evidence

    • John W. Eikelboom,
    • Eva Lonn,
    • Jacques Genest, Jr.,
    • Graeme Hankey,
    • and Salim Yusuf
    Ann Intern Med September 7, 1999 131:363-375

    This paper reviews the relation between homocyst(e)ine levels and risk for cardiovascular disease and the potential cardiovascular risk reduction associated with therapy to decrease homocyst(e)ine levels.

  • Potential New Cardiovascular Risk Factors: Left Ventricular Hypertrophy, Homocysteine, Lipoprotein(a), Triglycerides, Oxidative Stress, and Fibrinogen

    • Kishore J. Harjai
    Ann Intern Med September 7, 1999 131:376-386

    Recent studies have identified several potential new cardiovascular risk factors, including left ventricular hypertrophy, homocysteinemia, lipoprotein(a) excess, hypertriglyceridemia, oxidative stress, and hyperfibrinogenemia. This review summarizes the current literature that supports these conditions as risk factors.

Editorials

  • Homocysteine in Health and Disease

    • Ian Graham
    Ann Intern Med September 7, 1999 131:387-388

    Is an elevated plasma homocysteine level bad for you? Although the association between genetic hyperhomocysteinemia and vascular disease would clearly indicate that an increased homocysteine level precedes the disease, these issues have not been definitively resolved. Several papers in this issue address this topic.

  • Medical Writings Revisited

    • David R. Goldmann
    Ann Intern Med September 7, 1999 131:389-390

    The turn of the millennium will mark the end of the third year of the Medical Writings section in Annals. How successful has this section been, and what lies ahead for it?

Letters

  • Dietary Vitamin A Intake and Risk for Hip Fracture

    • Gunner Sigurdsson
    Ann Intern Med September 7, 1999 131:392

  • Dietary Vitamin A Intake and Risk for Hip Fracture

    • Håkan Melhus,
    • Karl Michaëlsson,
    • and Andreas Kindmark
    Ann Intern Med September 7, 1999 131:392

  • Vulnerable Plaque

    • Guha Krishnaswamy,
    • David S. Chi,
    • and Jim Kelley
    Ann Intern Med September 7, 1999 131:392-393

  • Vulnerable Plaque

    • James C. Doherty and
    • Marvin A. McMillen
    Ann Intern Med September 7, 1999 131:393

  • Vulnerable Plaque

    • Lanfranco de' Clari
    Ann Intern Med September 7, 1999 131:393

  • Vulnerable Plaque

    • Iftikhar J. Kullo,
    • William D. Edwards,
    • and Robert S. Schwartz
    Ann Intern Med September 7, 1999 131:393-394

  • Decrease in Endothelin-1 Plasma Levels during the Menstrual Cycle and after Ethinylestradiol Treatment

    • Gabriele S. Merki-Feld and
    • Paul J. Keller
    Ann Intern Med September 7, 1999 131:394

  • Correction: Cardiorespiratory Fitness, Impaired Fasting Glucose, and Type 2 Diabetes

    Ann Intern Med September 7, 1999 131:394

Medical Writings

  • Centennial Physician: Richard Perry, MD, Struggles with the Future

    • Fitzhugh Mullan
    Ann Intern Med September 7, 1999 131:395-398

    Richard Perry, MD, is a physician of the 20th century. He is effective, self-effacing, much loved—and embattled.

Medical Writings: Book Notes

  • Pulmonary Pathophysiology

    • Neil S. Cherniack
    Ann Intern Med September 7, 1999 131:399

  • Rehabilitation of the Patient with Respiratory Disease

    • Thomas L. Petty
    Ann Intern Med September 7, 1999 131:399-400

  • Evidence-Based Practice in Primary Care

    • Thomas McGinn
    Ann Intern Med September 7, 1999 131:400

  • Medicare Rules & Regulations: A Survival Guide to Policies, Procedures and Payment Reform

    • LouAnn Schraffenberger
    Ann Intern Med September 7, 1999 131:400

Ad Libitum

Book Listings

Medical Notices

  • Medical Notices

    Ann Intern Med September 7, 1999 131:0

Updates from the Annual Session

  • Update in Cardiology

    • Melvyn Rubenfire
    Ann Intern Med September 7, 1999 131:356-362

    The results of several studies published in 1998 were important to the practice of cardiology. The main areas of interest were evaluation of chest pain, acute coronary syndromes, valvular heart disease, congestive heart failure, and coronary risk factors.

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This Issue

September 7, 1999; 131 (5)
  1. Articles
  2. Brief Communications
  3. Reviews
  4. Editorials
  5. Letters
  6. Medical Writings
  7. Medical Writings: Book Notes
  8. Ad Libitum
  9. Book Listings
  10. Medical Notices
  11. Updates from the Annual Session

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