Update in Endocrinology
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
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•Type with double-spacing
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Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
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IN RESPONSE:
I agree with Heath and colleagues that the statement about marketing raloxifene for women at risk for breast cancer is a factual error. Raloxifene is indicated for prevention of osteoporosis in postmenopausal women at risk for bone loss. The other comments about fracture risk represent new information; the statement in the Update is not an error.
After our Update was submitted, presentations at the European Congress on Osteoporosis (September 1998) and a joint meeting of the American Society for Bone and Mineral Research and the International Bone and Mineral Society (December 1998) reported that raloxifene is effective in reducing vertebral fractures (1, 2). These data are encouraging, and clinicians await publication of the placebo-controlled clinical trial from which these data originate.
Finally, until the planned, prospective analyses of coronary heart disease events, electrocardiographic changes, and other cardiovascular events described by Heath and colleagues are published, it is not inappropriate to conclude that actual cardiovascular outcomes of treatment with raloxifene have not been measured.
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
- Copyright ©2004 by the American College of Physicians
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