Table of Contents

December 7, 1999; 131 (11)

Articles

  • Guanylyl Cyclase C Messenger RNA Is a Biomarker for Recurrent Stage II Colorectal Cancer

    • Burt Cagir,
    • Alyssa Gelmann,
    • Jason Park,
    • Tracy Fava,
    • Alexander Tankelevitch,
    • Edwin W. Bittner,
    • Eric J. Weaver,
    • Juan P. Palazzo,
    • David Weinberg,
    • Robert D. Fry,
    • and Scott A. Waldman
    Ann Intern Med December 7, 1999 131:805-812

    Expression of guanylyl cyclase C messenger RNA in lymph nodes is associated with recurrence of colorectal cancer in patients with stage II disease. Analysis of this expression by reverse transcriptase polymerase chain reaction may be useful for colorectal cancer staging.

  • HIV-1 Genotypic Resistance Patterns Predict Response to saquinavir–ritonavir Therapy in Patients in Whom Previous Protease Inhibitor Therapy Had Failed

    • Andrew R. Zolopa,
    • Robert W. Shafer,
    • Ann Warford,
    • Jose G. Montoya,
    • Phillip Hsu,
    • David Katzenstein,
    • Thomas C. Merigan,
    • and Brad Efron
    Ann Intern Med December 7, 1999 131:813-821

    In patients with failure of antiretroviral therapy that contains protease inhibitors, HIV-1 genotype is predictive of virologic response to subsequent therapy. This predictive capacity adds to that of standard clinical evaluation.

  • Effect of Clinician Communication Skills Training on Patient Satisfaction: A Randomized, Controlled Trial

    • Jonathan Betz Brown,
    • Myde Boles,
    • John P. Mullooly,
    • and Wendy Levinson
    Ann Intern Med December 7, 1999 131:822-829

    A continuing medical education program geared toward developing clinicians' communication skills was not effective in improving general patient satisfaction. To improve global visit satisfaction, communication skills training programs may need to be longer and more intensive, teach a broader range of skills, and provide ongoing performance feedback.

  • Internet Availability of Prescription Pharmaceuticals to the Public

    • Bernard S. Bloom and
    • Ronald C. Iannacone
    Ann Intern Med December 7, 1999 131:830-833

    The Internet may expand patient access to health-related services but at an overall increased cost. In addition, the quality of physician care over the Internet is uncertain, and potential for serious abuse exists.

Brief Communications

  • Chlorhexidine Compared with Povidone-Iodine as Skin Preparation before Blood Culture: A Randomized, Controlled Trial

    • Olivier Mimoz,
    • Amal Karim,
    • Alain Mercat,
    • Marie Cosseron,
    • Bruno Falissard,
    • Fabrice Parker,
    • Christian Richard,
    • Kamran Samii,
    • and Patrice Nordmann
    Ann Intern Med December 7, 1999 131:834-837

    Skin preparation with alcoholic chlorhexidine is more efficacious than skin preparation with aqueous povidone-iodine in reducing contamination of blood cultures.

  • Systemic Amyloidosis Presenting with Angina Pectoris

    • Jassim Al Suwaidi,
    • James L. Velianou,
    • Morie A. Gertz,
    • Richard O. Cannon III,
    • Stuart T. Higano,
    • David R. Holmes, Jr.,
    • and Amir Lerman
    Ann Intern Med December 7, 1999 131:838-841

    Cardiac amyloidosis can present as angina pectoris associated with coronary flow reserve abnormalities despite normal coronary angiograms. This finding may have major therapeutic and prognostic implications in patients with this disorder.

Updates

  • Management of Fibromyalgia

    • Lawrence J. Leventhal
    Ann Intern Med December 7, 1999 131:850-858

    Despite extensive clinical study, no distinct consensus has emerged on the optimal management of fibromyalgia. This paper discusses the diagnosis, pathophysiology, and treatment of fibromyalgia.

Position Papers

  • Selling Products Out of the Office

    • Gail J. Povar,
    • Lois Snyder,
    • and for the Ethics and Human Rights Committee
    Ann Intern Med December 7, 1999 131:863-864

    This position paper describes guidelines physicians should carefully consider when deciding whether to sell products out of the office and, if so, which ones.

Editorials

  • Changing Clinician Behavior: Necessary Path to Improvement or Impossible Dream?

    • Paul D. Cleary
    Ann Intern Med December 7, 1999 131:859-860

    In this issue, Brown and colleagues report that physicians who participated in a communications skills program believed that the program improved their skills, but patients did not. Methodologic considerations aside, the intervention may have been unsuccessful because behavior is hard to change.

  • Internet Purchase of Prescription Drugs: Buyer Beware

    • Jane E. Henney,
    • Jeffrey E. Shuren,
    • Stuart L. Nightingale,
    • and Thomas J. McGinnis
    Ann Intern Med December 7, 1999 131:861-862

    The Internet can be an important tool for providing health-related products, services, and information. As pointed out by Bloom and Iannacone in this issue, however, consumers must use this tool wisely. Until appropriate safeguards have been implemented, patients and practitioners should be cautious.

MMWR Supplements

  • 1999 USPHS/IDSA Guidelines for the Prevention of Opportunistic Infections in Persons Infected with Human Immunodeficiency Virus

    • USPHS/IDSA Prevention of Opportunistic Infections Working Group
    Ann Intern Med December 7, 1999 131:873-908

    In August 1999, agencies of the U.S. Public Health Service, in collaboration with the Infectious Diseases Society of America, published guidelines for preventing opportunistic infections in HIV-infected persons. These guidelines are reproduced here in an effort to reach all internists who care for HIV-infected patients.

Letters

  • Inhaled Corticosteroids or Antileukotrienes for Asthma?

    • Neil B. Hampson
    Ann Intern Med December 7, 1999 131:865

  • Inhaled Corticosteroids or Antileukotrienes for Asthma?

    • Theodore F. Reiss
    Ann Intern Med December 7, 1999 131:865

  • Breast Symptoms in a Health Maintenance Organization

    • Stephen Doral Stefani and
    • Luciana Cadore
    Ann Intern Med December 7, 1999 131:865

  • Breast Symptoms in a Health Maintenance Organization

    • Mary Barton,
    • Suzanne Fletcher,
    • and Joann Elmore
    Ann Intern Med December 7, 1999 131:865-866

  • Olestra Snacks Compared with Regular Snacks

    • Michael F. Jacobson
    Ann Intern Med December 7, 1999 131:866

  • Plasma Exchange for Hemolytic Crisis in Wilson Disease

    • Akira Matsumura,
    • Hideyuki Hiraishi,
    • and Akira Terano
    Ann Intern Med December 7, 1999 131:866

Medical Writings

  • “Memes” as Infectious Agents in Psychosomatic Illness

    • Stephen E. Ross
    Ann Intern Med December 7, 1999 131:867-871

    Can a mere idea cause medical pathology? Some disease conceptions appear to induce illness in the absence of any classic pathogen. These psychosomatic memes induce biological, psychological, and social changes in their hosts, and they can be transmitted to others.

Medical Writings: Book Notes

  • Coronary Artery Disease in Women: What All Physicians Need To Know

    • Richard M. Steingart
    Ann Intern Med December 7, 1999 131:872

  • Clinical Evidence: A Compendium of the Best Available Evidence for Effective Health Care

    • Lawrence G. Smith
    Ann Intern Med December 7, 1999 131:872

Book Listings

Medical Notices

  • Medical Notices

    Ann Intern Med December 7, 1999 131:0

Summaries for Patients

  • A New Test for Recurrent Colon Cancer

    Ann Intern Med December 7, 1999 131:805

  • Drug Resistance Tests to Predict Response to Treatment for HIV Infection

    Ann Intern Med December 7, 1999 131:813

  • Communications Skills Training for Health Care Providers and Patient Satisfaction

    Ann Intern Med December 7, 1999 131:822

  • Buying Prescription Drugs over the Internet

    Ann Intern Med December 7, 1999 131:830

  • Comparison of Two Antiseptic Solutions To Disinfect the Skin for Blood Cultures

    Ann Intern Med December 7, 1999 131:834

  • Chest Pain as an Unusual First Symptom in Patients with Systemic Amyloidosis

    Ann Intern Med December 7, 1999 131:838

Updates from the Annual Session

  • Update in Geriatrics

    • William J. Hall
    Ann Intern Med December 7, 1999 131:842-849

    This Update contains information that is directly applicable to primary care practices, where internists see an ever-increasing number of older persons. The topics covered are dementia and Alzheimer disease, osteoporosis, cardiovascular risk, antidepressant therapy and falls, incontinence, and pain.

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This Issue

December 7, 1999; 131 (11)
  1. Articles
  2. Brief Communications
  3. Updates
  4. Position Papers
  5. Editorials
  6. MMWR Supplements
  7. Letters
  8. Medical Writings
  9. Medical Writings: Book Notes
  10. Book Listings
  11. Medical Notices
  12. Summaries for Patients
  13. Updates from the Annual Session

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