Extrahepatic Manifestations of Hepatitis C Virus Infection
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TO THE EDITOR:
Two extrahepatic manifestations of HCV should be added to those described in the recent review by Gumber and Chopra [1].
A significant prevalence of HCV markers (5% to 20%) has been reported in several series of patients with polyarteritis nodosa [2-4]. This finding suggests that HCV may occasionally cause this disorder. Cases of autoimmune thrombocytopenic purpura have been noted in patients with chronic hepatitis C. Serum HCV antibodies have been detected in 19% of 112 patients with autoimmune thrombocytopenic purpura [5].
Thus, HCV markers should be monitored in patients with polyarteritis nodosa and autoimmune thrombocytopenic purpura.
Jeffrey L. Pollock, MD
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
- Copyright ©2004 by the American College of Physicians
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