Predisposition to Cytomegalovirus Infection of the Gastrointestinal Tract

  1. Neil L. Kao, MD; and
  2. G. Wendall Richmond, MD
  1. University of Illinois College of Medicine; Rockford, IL 61107-1897 Rush Presbyterian-St. Luke's Medical Center; Chicago, IL 60612-3833

    The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:

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    TO THE EDITOR:

    We read with interest the review by Goodgame [1] because one of our patients with systemic lupus erythematosus experienced cytomegalovirus infection complicated by a colonic perforation. I do not believe that therapy with corticosteroids alone encourages the development of widespread cytomegalovirus infection [2]. However, the addition of cytotoxic drugs such as cyclophosphamide, azathioprine, or cyclosporine may reactivate latent infection, as in our patient [3, 4]. Appreciating this association may help clinicians recognize and make an early diagnosis of cytomegalovirus infection in predisposed hosts.

    Neil L. Kao, MD

    University of Illinois College of Medicine; Rockford, IL 61107-1897

    G. Wendall Richmond, MD

    Rush Presbyterian-St. Luke's Medical Center; Chicago, IL 60612-3833

    The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:

    •Include no more than 300 words of text, three authors, and five references

    •Type with double-spacing

    •Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.

    Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.

    Annals welcomes electronically submitted letters.

    References

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