RSS Feeds
CD4 Counts as Surrogate Markers for Progression to AIDS
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•Type with double-spacing
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Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
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TO THE EDITOR:
Choi and colleagues [1] tell us that asymptomatic patients receiving zidovudine do better, although their CD4 counts do not improve substantially. On the other hand, preliminary analysis of the Concorde trial [2] indicates that patients derive no benefit from early treatment with zidovudine, although their CD4 counts are much higher. Why does zidovudine stimulate lymphocytes in the United States but depress them in Europe? Perhaps zidovudine confuses lymphocytes as much as it does doctors and patients.
B. Hirschel, MD
Hopital Cantonal Universitaire de Geneve; CH-1211 Geneve; Switzerland
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
- Copyright ©2004 by the American College of Physicians
