Do ACE Inhibitors Affect Diabetic Morbidity and Mortality?
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TO THE EDITOR:
In his discussion of angiotensin-converting enzyme (ACE) inhibitors and diabetic nephropathy, Bakris [1] implies that ACE inhibitors ultimately reduce the need for dialysis. Although ACE inhibitors have been shown to alter the rate of progression of proteinuria and preserve renal function, as stated by Bakris, I am unaware of data showing any change in morbidity or mortality rates. The assumption that morbidity and mortality rates will be affected is certainly logical, but we have been burned many times by similar past assumptions.
Gerard S. Brungardt
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
Include no more than 300 words of text, three authors, and five references
Type with double-spacing
Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
- Copyright 2004 by the American College of Physicians
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