LETTER
Immunosuppressive Effect of Zidovudine
Edward K. Chapnick;
Douglas V. Sepkowitz; and
Jeremy D. Gradon
1 April 1993 | Volume 118 Issue 7 | Pages 571-572
TO THE EDITOR:
We read McLeod and Hammer's review [1] on zidovudine with great interest. The authors state that there has been one reported case of zidovudine-induced hepatitis [2]. We wish to call to your readers' attention another case, which we reported in 1992 [3], further emphasizing the need to consider this agent in the differential diagnosis of hepatitis in HIV-infected patients.
1. McLeod GX, Hammer SM. Zidovudine: five years later. Ann Intern Med. 1992; 117:487-501.
2. Dubin G, Braffman MN. Zidovudine-induced hepatotoxicity. Ann Intern Med. 1989; 110:85-6.
3. Gradon JD, Chapnick EK, Sepkowitz DV. Case report. Zidovudine-induced hepatitis. J Intern Med. 1992; 231:317-8.
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